This ??breathable air-pumping cushion comfortable shoe?? has sufficient ventilating function and soft air cushioning function as well by installing air room and air circulation way in the outsole and taking in and circulating fresh outside air inside the shoe while walking with the application of air-pass technology. The air contained in the air room of the outsole is compressed when the shoe touches the ground in the process of walking, and the compressed air is pushed inside the shoe through the ventilating hole in the midsole. Then, when the shoe is raised in the air, the compressed air room of the outsole is restored to its original state with the intake of outside air through the air-inhaling hole located in the rear of the shoe. Such a process is repeated while walking so as to circulate fresh outside air inside the shoe continuously and also provide soft and comfortable sense of cushion with the air-pumping cushion made by repeated contraction and recovery of the outsole. With the intake and circulation of fresh outside air, the shoe is helpful to the prevention of Diabetic Foot Disease by restraining malignant microbes, getting rid of foot odor, improving blood circulation, overcoming foot fatigue, and making foot soft and comfortable with the air-pumping cushion function of the outsole.