ZEDIGUS - manufacturing technology of smart drugs NanoHApAM- Antibiotic-PEG to treat severe wounds: purulent, gunshot and diabetic foot. Innovative of high-tech and competitive (smart) drugs for targeted delivery of antibiotics (effect Biointerface), recovery matrix (Matrix). Needs of the global market for drugs NanoHApAM-Antibiotic-PEG to treat severe wounds are over $ 3 billion and millions of patients who need these drugs.